Infectious Disease
Also known as: Rapid Plasma Reagin, Venereal Disease Research Laboratory, Nontreponemal tests
If you have symptoms of syphilis such as sores (chancres), rashes, or flu-like symptoms, or if you have been exposed to syphilis, contact your clinician immediately for evaluation and testing.
The RPR and VDRL tests look for special proteins in your blood. Your body makes these proteins if you have syphilis. These tests are like a first check. They help find out if you might have this infection.
Doctors order these tests to look for syphilis. Syphilis is a sickness you can get from sex. They often use these tests if you have symptoms. They also use them if you have been near someone with syphilis. Sometimes, these tests are part of regular checks during pregnancy.
Syphilis screening tests like RPR and VDRL are typically reported as 'reactive' (positive) or 'non-reactive' (negative), often with a titer (e.g., 1:8). Interpretation depends on the specific lab, clinical context, and whether it's a screening or follow-up test.
Clinical Reference
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Educational purposes only — This information is not a substitute for professional medical advice, diagnosis, or treatment. Always discuss your lab results with your healthcare provider.